2.
P. Aladashvili, N. Gegeshidze, V.
Sharabidze. National center of tuberculosis and lung diseases. Tbilisi.
Usage
of extra corporal membrane oxygenation, hemabsorbtion and other extra
corporal detoxic methods in treatment of patients infected with
tuberculosis.
Summary.
The article deals with the usage of
extra corporal membrane oxygenation, hemabsorbtion and other extra corporal
detoxic methods in treatment of patients infected with tuberculosis. As a
result of the research the following conclusions were made:
·
The above-mentioned
method is a procedure which causes fewer traumas. It may be used with
different forms of tuberculosis.
·
EMO+hemabsorbtion,
lasotherapy and ultraviolet ray of blood improves both blood reology and
perfusion of the bodies, and thus minimizes the possibility of recidiv
development.
·
Increase of immunity and
blood elements, especially T and B lymphocyte level, favors decrease of
quantity of medicines as well as durance of treatment.
3.
Alibegashvili
M., Kitiashvili I., Managadze L., Chigogidze T., Kotrikadze N.Iv.
Javakhishvili Tbilisi State University, Faculty of Biology, Faculty of
Medicine.
Investigation
of lipid spectrum of blood erythrocyte membranes in patients with prostate
tumors.
Summary.
Lipid content of erythrocyte
membrane, especially phospholipids, cholesterol and lipid peroxidation
intensity in patients with prostate benign hyperplasia and prostate
adenocarcinoma has been investigated.
In addition to the increase of total amount of phospholipids, corresponding
rise of cholincontaining phospholipids portions and decrease of
aminocontaining phospholipids has been observed.
In both pathologies the increase of cholesterol quantity and intensity of
lipid peroxidation has been established. Obtained data must be contributed
to the systemic character of tumors.
4.
L. Akhvlediani, N. Porakishvili, O. Chakhoiani, Dj.
Kikava. TBilisi State University, Batumi State University, Medical centre of
Sailors, Batumi.
Autoantibodies Opposed human chorionic gonadotropinin in patients with
malignant and benign tumor
Abstract.
The patient
with ovarian histoma
and uterus cista showed the highest
titre of anty-hCG
autoantibodies out of the patients
studied.The patient with malignant
tumours hed
non-appreciable levels of anti-hCG antibodies.
However a correct measurement of the serum
hCG β is technically complex which limits
its application for tumour screening.
the serum expression of hCG
in malignancies may lead to the induction of specific
autoantipodies,which can represent a beeter
serum marker.In addition it will demonstrate a
possibility of a recognition of the tumor- associated antigens.
5.
Andriashvili, Therapy House.
LTD. Tbilisi.
Usage of the principles of
anthroposophical Medicine, in treafment of Bronchial Asthma.
Summary. The aim of presented
study is to scientifically evaluate effectiveness of anthroposophic
methods of asthma treatment, taking into account
individual and recovery potential of the
child based on salutogenetic theory.
The research was performed by open controlled
clinical observation of the target group.
30 patients of the same sex, age and clinical form/stage
of disease were studied.
Three groups were identified among them:
1. Group 1 - classical methods of treatment
2. Group 2 - classical and anthroposophic methods of
treatment
3. Group 3 - anthroposophic methods of treatment only
We have performed the evaluation of effectiveness
of the anthroposophic methods of
treatment on the basis of short-term and long-term (3-5
years) observation of the
patients.
Clinical presentation and immunological status of
pediatric patients with remission of
symptoms and exacerbated asthma were evaluated in all
target groups.
The study
will be continued for two years in order to achieve the reliability of
scien tifi-
cally valid results. Continuation of the study
aims to include proposed antropho sopic
method in treatment plan of pediatric patients.
6.
Z. Antadze, M.
Kukava.Chair of Neurology, Center for Medical-Biological Studies.
Tbilisi. SEVERAL SPECIFICATIONS OF
POSTTRAUMATIC STRESS DISORDERS
SUMMARY. The study purposed investigation of 110 war refugees from
Abkhazia. In the most cases (70,9%) pronounced and prolonged PRSD had been
revealed, which were conditioned by marked disfunction of psychosocial
sphere. As a rule, PRSD was accompanied by sympathicotonia, insomnia and
psychosomatic manifestations, expressed in a form of arterial hypertension
and the chronic headache attacks.
7.
N. Atuashvili, G.
Osmanova, A. Pavliashvili. National Centre of Oncology. Tbilisi; V.
Khositashvili, Z. Chakseliani, L Khositashvili. Research
Institute of Radiology and Ecology of Agriculture. Tbilisi.
Prevention and therapy of radiation sickness with medicament
“Forest Gift”
Summary.
Instruction for using “Forest Gift. “Forest Gift” is a 50%
sugar syrope of a neutral vegetative extract. It contains proteins, free
aminoacids. vitamins, alcalydes, lipids, phitosterins, phenol mixtures,
chlorophyle and other biologically active mixtures.
It is used in medisine as a radioprotector, for radiation theraphy of
different kinds of tumours, treatment of vegetoneurosis and infections
illnesses, and as a remedi for protection from irradiation.
“Forest Gift” is registered and certificated by the Ministry successfully
used for the rediation theraphy in the Oncological Centre of Georgia.
8.
V.Bakuradze, T.Chigogidze, V.
Sulhanishvili. National Center of Urology, Tbilisi, Georgia.
Changes of renal local blood flow in
acute hemorrhage and sepsis
Summary. We investigate the
renal local blood flow (RLBF) in cortical (CZ), subcortical (SCZ) and
medular (MZ) zones of the rabbits in acute sepsis and hemorrhage using H2
clearance method.
In sepsis conditions we observed decreased RLBF in CZ and SCZ and relative
increase in MZ. In case of acute hemorrhage and gram-positive sepsis RLBF
was reduced in all zones. These changes were more severe in case of acute
hemorrhage and gram-negative sepsis. We confirm that in cases of acute
hemorrhage or / and sepsis kidneys undergo deterioration of blood
circulation in all zones.
9.
K. Beltadze, M Kiziria, Al. Tsiskaridze, R Shakarishvili. Tbilisi State
University, Faculty of Medicine, Department of Neurology and Neurosurgery.
Diagnostic of acute leukoencephalopathies.
Summary.
Recent advances in neuroimaging have markedly expanded the spectrum of
diseases, known as rarities in the nearest past among them, to be considered
by the clinician in the process of diagnostic workup. The presented case
warns practicing neurologist about potential diagnostic collisions appearing
in case of either underestimation, overestivation or proper correlation of
clinico-anamnestic and neuroimaging data.
10. Bochorishvili, N. Bregvadze. State Medical Academy of
Postgraduate Education, Tbilisi. Clinic case of
cytomegalovirus encephalitis.
SUMMARY.
Many epidemiological stadies have confirmed that severe congenital CMV
disease resalts mainly from primary CMV infection in pregnant women. We
discass the case of intrauterine CMV infection in 9 month child born from
supposedly primary infected mother. Hence it is recommended that women of
childbearing age know their CMV serostatus. In women with confirmed primary
infection amnionic fluid PCR can be used to assess the risk of CMV diease
for fetus. In case of confirmed acute infection of fetus the abortion is
only way out. Also it is recommended to diagnose CMV infection in newborn,
by detection of spesific IgM antibodies and to administer immunoprophylactic
11. I. Bregvadze, M.
Korkelia.
State Medical Academy of Postgraduate Education, Tbilisi.
Neurotic Development and Dysthymic
Disorder.
Summary.
The article describes a clinical case that argues diagnostic criterions,
appropriated to Dysthymic disorder in the historical attitude. The
thoughtful differtial diagnostics in between dysthymia, cyclothymia,
schizophrenia and personality disorder is conducted.
e-mail:
datoch@magtigsm.ge
12.
T.Z. Bregvadze, S.I.
Tabagari; Tbilisi State University, Geography-Geological Faculty, «AIETI»
Medical School;
“Geographic
Information Systems for Public Health and Epidemiology”.
13.
M.Burduli, G.Tabidze, M.Iakobashvili, N.Mamamtavrishvili,
A.Gogishvili, E.Narsia.
Tsinamdsgvrishvili Institute of
Cardiology, Tbilisi, Georgia.
Treatment Tactics
for Patients wit Type II Diabetees Melitus
55 patients with
initially developed Diabetes Melitus have been examined. Lypid spectrum and
glikemia were studied during 24 hours on the background of combined therapy
with the use of micronized form of maninil/siopfor mix. Positive dinamic of
the lipid spectrum was observed on the background of compensation of
diabetes, which leads to a certain decrease of negative consequences of
cardiovascular defects of patients with Diabetes Melitus Type II, Ishhemic
heart disease, and arterial hypertension.
14.
I.
Burdzgla. Otoacoustic Emission and its Clinical Application
Summary.
The discovery of the phenomenon of otoacoustic
emission (OAE) has dramatically changed the opinions on the functioning of
the inner ear. The OAE is a sound of very low intencities which can be
registered by means of a sensitive microphone in the outer auditory canal.
Two main types of OAE have been identified – spontaneous and evoked. It has
been established that the transient-evoked OAE ( TEOAE) is highly specific
and characteristic for individual subjects. Moreover, it has been shown that
TEOAE differs in the right and left ears of the same person. The conducted
studies have been proved that TEOAE is a stable event. The TEOAEs of the
same patterns were registered in our investigations when the intervals
between separate tests were rather long – days, weeks or even months. The
TEOAE is widely used in clinical audiology as the screening test of the
hearing. Due to the peripheral origin, by TEOAE recordings it is possible to
estimate the state of cochlea and to reveal the hearing pathology in
newborns of the risk groups.
15.
M.
Chkhaidze. Chair of Urology
at Medical Academy. Optimization of Hemostasis in TURP-operations by means of “Buta”
Summary
It is described the new method for prevention of
bleeding and TUR-syndrome by means of polymer substance “Buta”. The results of
experimental (on 17 dogs and 10 rabbits) and clinical investigations (on 40
patients) show that the substance “Buta” preliminary injected into the prostate
during the TURP operation undergoes a deep polymerization by the contact with
the hot loop of resectoscope and creates a thin film on the resected surface of
prostate, which embolises the small and middlesized blood vessels and prevents
both the bleeding and absorption of irrigative fluid and TUR-syndrome.
Peculiarities and advantages of the described method are discussed.
16.
A.
Chkeidze, L.Sturua, G.Kakauridze
Standards of laserotherapy in obstetrics.
Summary
With the aim of increasing the effectiveness of a
treatment process lasertherapy has been widely used in feto-maternal medicine.
The most widespread and broadly applied type of laser radiation is a helium-neon
laser (wave length-632,8 nm). Basic methods of lasertherapy. Treatment of
pregnants by a laser beam is not in all cases of a monotherapeutic character and
is applied in combination with medical preparations in minimum doses. At this
stage the major objective is to exclude unfavourable collateral effects of
mediactions on maternal organism, lessening of pharmacological load on fetal
organism
17.
K Dadiani, I Pagava, N. Pilia, I Beraia, N. Menagarishvili, N.
Chakvetadze. Natadze's Research Institute of Sanitary and Hygiene.
Elaboration
urgent measures of state regulation system in food industry.
SUMMARY
The
article reviews actual problems, resolution of which would decrease possible
adverse impact of genmodified food in case of their possible accesse on the
Georgian market.
18. L.
Dateshidze. Institute of Medicinal Plant.
"Georgian
pharamceutical market and marketing of pharmaceutical preparations in
Georgia".
19.
Djaparidze N. Khardzeishvili O. Patologic Anatomy Department of the Georgian Medical
University of Tbilisi.
Feature of the distribution T and B lymphocytes in stroma of the endometrium
with glandular hyperplasii, adenomatose and highly differenciated
adenocarcinoma.
Summary.
The authors
has studied the quantity and peculiarity of lymphocites in stroma of the
endometrium with glandular hyperplasii, adenomatose and highly
differenciated adenocarcinoma. The material consisted 26 uterine abrasio of
the women with dysphunctional uterine bleeding. Accoding these
investigasion with morphometrial studi of the character quantity and
localization of the lymphocites. There are differents among the quantity of
the lymphocites by these condicions. The lowest quantity of lymphocits is
registered by glandutar hyperplasia, the highly quantity of lymphocits by
highly differenciated adenocarcinoma.
In endometrium situated are presented solely by T lympocits, as to B
lympocits they are absentin.
Number of CD-4 (T helper) and CD-8 (T suppressor) increase by highly
differenciated adenocarcinoma.
The increase of T-lymphocytes with the growth of grandular anaplasii and
epithelium of mucous membrane of uterus in explained by a change in genetic
specificity of ephiteliocytes and the emergence of their population with
different antigene properties having lost the tolerance towards their own
immune system
In the most probable that the antigene difference grows with the increase of
anaplasii level, first manifasted by tissue atipia (glandular hyperplasii)
and then turns into cellular atipia (adenomatose and highly differenciated
adenocarcinoma).
20. L. Dolidze. Batumi Central Clinic Hospital.
TRANSURETHRAL ELECTRORESECTION OF PATIENTS WITH URINARY
BLADDER CANCER.
THUS WIDE INTRODUCTION OF TUR ENABLES
CONSIDERABLY CHANGE THE STRUCTURE OF RENDERING
ASSISTANCE TO THE PATIENTS SICK BY URINARY BLADDER CANCER.
THIS METHOD HAS A
DEFINITE ADVANTAGES IN COMPARISON WITH OPEN OPERATION ON URINARY
BLADDER SLIGHT INJURY, GOOD VISUAL AND ULTRASONOGRAPHICAL CONTROL OF
COMPLETENESS OF RESECTION, ABLASTIC CONDITION WHILE MANIPULATIONS IN
ISOLATED CAVITY OF URINARY BLADDER.
21.
N.A. Dvaladze, B.A.
Mosidze, T.F. Bochoidze,
N.Sh.Chkhetia.
Eristavi
National Center
of Experimental and Clinical Surgery
Immunocorrective
photohemotherapy
in surgical treatment of patients with lung cancer.
Analysis of the treatment of 350 patients with lung cancer is proposed
in the study.
In virtue of wide immunologic monitoring of the immune status of the
patients with lung cancer has been reserched.
Results of our study showed presence of immunodeficiency at the cellular
link of immune system for patients with lung cancer. It increased
togeather with progressing the disease and was
characterized by rising the suppressive activity, lowering the ratio –
Th/Ts, depressing the
sensibilization of lymphocytes to the normal
tissular (NA) and tumor antigens (TA), and decreasing the activity of
the NK – and phagocyting cells.
Analysis of correlation between the immunologic status before operation and
the effectiveness of surgical treatment, conducted by a
method of the grouping and the discriminative analisis,
has revealed direct correlation between the LS –
lymphosytes to NA and the survival of the patients with lung cancer.
This analisis and initial low NK
activily with association to a bad prognosis
lead to necessity for using the immunocorrection.
Quantum hemotherapy in certain regimes of
photomodification of blood have been found as an
effective remedy for immunocorrection. It was
displayed by reducing the cancentration of
T-suppressors, rising the ratio
Th/Ts, increasing the activity of the NK – and
phagocyting cells. Taking the anti-inflammatory
and antioxidantive action into account, the
quantum hemotherapy should be considered as an
effective remedy for preventing and treating the operative and
post-operative complications, as well as a remedy for
rising the resistance of the body of a patient with lung cancer to
the radial and chemotheraputic treatments.
b.mosidze@access.sanet.ge
22. K. Ediberidze.
A.Natishvili Institute of Experimental Morphology Georgian Academy of
Sciences Tbilisi, Georgia.
Ultrastructural peculiarities of human
placenta in incomplete pregnancy of hormonal genesis.
Summary.
Complex histologic and
election microscopic study of placenta is performed in 40 women with
incomplete pregnancy (20-27 weeks). Inflammatory and dystrophic changes,
also early immaturity of the stroma were described.
23. G. Galdava. Research Institute of skin and venereal diseases. Tbilisi.
Some pecularities of
secondary infertility in man.
Summary. From
all the abovementioned we can conclude, that the development of secondary
infertility in man is caused by variety of different factors. Research has
revealed , that 45,6% of cased of secondary infertility are caused by
sexually transmitted diseases and infectuas processes of urinaru and sexual
organs; 12% of cases are caused by auto-immune processes that occur in
organisms of man, and 3,2% of cases are triggered by unfriendly environment,
and unsetisfactory working and living conditions. Timely identification of
the above factors and adecuate treatment and preventive measures shall
provide for substantial dicrease of overall rate of secondary infertility in
man.
tel.
899 507065, 961146
e-mail:ggaldava@hotmail.com
24.
R. Gakhokidze. Department of
Bioorganic chemistry of Tbilisi State University, Chavchavadze ave, 1,
Tbilisi, 380079, Georgia.
Bioorganic Chemistry and Adaption of Human with
Environmental
There are two ways
of adaptation of human with environmental. The first - improvement of
environmental preservation, the second - increase the stability of organisms
towards the action of harmfull factors on the basis of the methods of
bioorganic chemistry.
Adaptation of organisms to the different conditions is possible through the
usage of bio-energo-activators, which were obtained in our laboratory.
Bio-energo-activator enables preservation of homeostasis through activation
of physiological regulatory mechanisms, providing adaptation to the extremal
conditions.
In our
laboratory on the basis of bio-energo-activators many highly-effective
medical preparations have been created. Namely an ,,Vitarag'' ointment,
which contains ecologcially pure biological products, is used in cases of
inflamatory, parulent and fungal diseases, for trating furunculus, burns,
arthritis, myositis, mastitis, red wind, diseases of mucosal layer of nasal
and oral cavities, piles, erosion and ulcar of uterine cervix. It
accelerates healing of wounds, it stops alopecia, skin aging, destroys
wrinkles and swelling of periorbital areas.
A unique drug "Ramer"
has been created for regulating homeostatic curing neurosis,
hypertension, increases mental, physical and sexual potention, has
general rehabilitation effect, it strengthens the organism's resistance
against diseases and external factors.
Tel.: (995 32) 22 50 30; (995 32) 25 15 53
FAX : (995 32) 25 1876
E-mail : rgakhokidze@hotmail.com
25.
K. GOGILASHVILI., E. JAPIASHVILI., L.
ZHORZHOLIANI. QUONTITIVE AND
QUOLITATIVE RISK FACTORS RANGING IN HYPOPLASIA DEVELOPMENT.
SUMMARY. The present research aimed at integral study and
assessment of risk factors promoting spread and
formation of hypoplasia among children. The survey covered 617 Georgian
children at 6-16 years of age. Dental status was determined by standard
scheme designed by WHO. Data were processed
according to SPSS/v.9 (statistical package for social sciences) program
package.
Through the rating of the identified risk factors it was concluded that
the most significant influence over the development of enamel hypoplasia are
caused by unbalanced nutrition, excessive use of carbohydrates, hereditary
predisposition to hypoplasia, artificial nutrition under one year age,
mothers sickness during the pregnancy, accompanying somatic diseases and
pathologic proceeding of the pregnancy
.
26. N. Gurgenidze,
M.Khinikadze. Batumi N1 Hospital’s clinic of Neurology&Neurosurgery.
Fixatives and endoprotheses of Titan Nickelid
with thermomechanical memory of form.
In Batumi N1
hospital’s clinic of Neurology&neurosurgery firstly in Georgia were used
ficsators and endoprotesis from TiNi with thermomechanical memory of form
in case of vertebro-spinal injuries and diseases.
27.
Gvakharia G. Nakaidze B. Gagua Z. Dandurishvili S.Iv.
Javakhishvili State University Surgical Department.
The
Diagnose And Treatment Of Diapragmh Post-Traumatic Hernia
During the traumatic inguar of the abdomen and the chest
hole, the diapragmh destruction is a comparativeli rare patologhy. We
represent the three cases of diapragmh post-traumatic hernia, complicated
with a stuck. The thoracoabdominal way of the operation was chosen. The
stomach, spleen and a small intestine loop were stucked. It was done a
gastrectomia, splenectomia, and in the third case-the stomach detorzio. All
three operations were finished by the bringing down the organs in the
abdomen, diapragmhoraphy and the drenning of the abdomen and chest.
28.
I. Jashi, B. Kobulia M. Tsinamdzgvrishvili’s
Institute of Cardiology, Tbilisi, Georgia. Comparative Effects of Losartan and Enalapril on
Renal Function and Hemodynamics in CHF
Summary
The aim of investigation was the evaluation of
Enalapril (E) and Losartan (L) influence on electrolyte and water excreation,
renal function and renal hemodynamics in pts with congestive heart failure (CHF)
in accordance with initial hemodynamic status.
83 male pts, aged 44 to 67, with CHF (II-III NYHA
classification) due to chronic forms of coronary heart disease were examined.
The pts were divided in 3 groups depending on the treatment: I group (29 pts)
received cardiac glycosides and diuretics; E 10 mg bid was administered to 28
pts (II group) and L 12,5 mg once daily, titrated to 25 mg, and up to 50 mg once
daily was administered – to 26 pts (III group). Acute pharmacological test
followed by six-month course of E or L treatment was performed in each pts.
Renal function was assessed by endogenous creatinine clearance, renal
hemodynamics parameters – by cardiotrast clearance. Sodium and potassium ion
concentration was determined by biochemical analyzer, sodium and water excretion
was calculated by formula. Central hemodynamic was determined by
echocardiography, tetrapolar rheography.
After six-month of treatment both E and L improved
NYHA class, 6-minute walk distance, and quality-of-life scores (all p<0,05 from
baseline), and there were no differences between the 2 treatments.
Increased glomerular filtration rate (GFR) and
effective renal blood flow (ERBF) were observed in the course of treatment with
E (GFR – 68+1 ml/min before treatment vs. 71+2 ml/min after
treatment, p<0,05; ERBF – 621+16 ml/min vs. 781+12 ml/min, p<0,01,
respectively). E increased renal sodium and water excretion accordingly by
32.1-74.3% and 21.3-64.6%. The renal vascular resistance decreased by 16.2%. The
change in the L group was significantly greater than in the E group, especially
about concerning ERBF and renal vascular resistance.
Our results show, that beneficial effects of E or L
on renal function and hemodynamic parameters were due to direct renal action of
the drugs (selective renal vasodilation due to angiotensin II inhibition).
Improved natriuresis and diuresis, decreased the rigidity of vessel’s wall,
which was marked in CHF due to high sodium concentration, and also decreased the
compression of vessels due to interstitial edema. Decreased renal vascular
resistance. This course the potentiation of vasodilation. After six-month E and
L treatment subjective complaints and objective symptoms of CHF decreased and
tolerance to physical activity increased. Both drugs treatment reduced the
functional class of CHF, which helps the rehabilitation of pts.
29. Sk. Jgushia, L. Jorjoliani -MD., Ph.D.; R.
Karseladze –MD., Ph.D.; N. Tskhakaia-MD.;M. Kelengeridze, T. Macharashvili, Institute of Pediatrics
The realization of Asthma Educational Program in the base of “Asthma-School”
SUMMARY
The pediatric
asthma-school has been established for the purpose of appropriate medical
education and enhance of access to health check information, as well as for the
mastering in self-help and self-control methods for patients with asthma and
their family members.
The efficacy of educational program in asthma-school was estimated by dynamic
inspection of 105 patients with bronchial asthma. The age of children was 6-15.
Individual programs for education of patients and their parents (in accordance
to the parents’ approval), which included lessons with the patients and their
parents according with the form and severity of the disease, were completed. The
length of each lesson was 50-60 minute and the extent of each course was 10-12
lessons .The education course consisted of academic lectures and
conversations (Questions- answers) between patients, their parents and the
Asthma-school members.
12 months after the end of the educational
process, the connection of patient and his family members’ knowledge in
management of Asthma and as a result, the positive dynamics of subjective and
objective symptoms of the disease could be observed. There was a significant
improvement in the condition of patients, as well as decline here the index of
disease from 13,5 + 0,7 to 5,1+1,1 at the end of the educational round.
Thus, as a consequence of Asthma education
there was developed not only the improvement of the basic knowledge of asthma
among the patients and their relatives, but also, the progression in dynamics of
the subjective and objective findings of the disease.
e-mail:
marika2posh@yahoo.com
30. P.
Kalandadze. Chair of Urology at Medical Academy.
The modern aspects of bladder
reinnervation
Summary.
The article represents the
literary review of modern methods of treatment of the
neurogenic dysfunction of the bladder in spinal cord injured patients
and of methods of the bladder reinnervation.
The author concludes, that the most of current
methods of treatment are symptomatic and less effective. The methods of
bladder reinnervation: implantation of a sacral
anterior root stimulator and operation of
ileo-vesicopexy, represent the way of
pathogenetic treatment and are much more effective and perspective.
31.
G.
Kamkamidze, M. Butsashvili, N. Gamkrelidze, K. Barabadze, T.Churadze.
Pediatric Clinic of the Tbilisi State Medical University. Infectious
Diseases, AIDS and Clinical Immunology Research Center. Research Institute
of Pediatrics. Role of human herpesvirus-6
infection in children with fever and rash.
Summary.
Human herpesvirus-6
(HHV-6) is one of the recently discovered herpesviruses. Primary HHV-6 infection
is causative agent of roseola infantum, one of the diseases of childhood
characterized by the development of fever and rash. The goal of our study was
the evaluation of the role of primary HHV-6 infection in children with fever and
rash. 32 children 6 months – 5 years of age with fever and generalized rash who
have been tested to be negative on measles and rubella antibodies were enrolled
in the study. Anti-HHV-6 IgM and IgG antibodies as well as HHV-6 DNA were
detected in these groups by ELISA and PCR methods correspondingly. Primary HHV-6
infection has been found in 11 out of 32 patients (34,4%) from the study group
vs. none in the control group (p<0.001). Primary HHV-6 infection is associated
with fever and rash in the early childhood and it has to be considered during
the differential diagnosis of the diseases with rash.
32.
N. Kandelaki, M.
Sosiashvili, M. Tskhadaia. Scientific-research
Institute of Pediatrics. Tbilisi. GEORGIA. STRUCTURAL AND CYTOCHEMICAL
PECULIARITIES OF ERYTHROCYTIES I N
CHILDREN WITH ATOPIC BRONCHIAL ASTHMA.
It is known that bronchial asthma is the
chronic inflammatory disease and that among other peripheral blood cells,
erythrocytes have great importance to be investigated to understand the
pathogenesis of this process.
To estimate the efficacy of treatment before and
after ZADITEN administration on the basis of structural and cytochemical data
total 80 patients with atopic asthma were examined. Children with atopic asthma
were divided into two age groups. We made morphological and cytochemical studies
of peripheral blood erythrocytes in acute period of illness-before and after
treatment. Our material we investigated with the use of method of direct
erythro-cytometry and with the aid scanning electron microscopy. In the material
the erythrocytes are presented differently before and after treatment. It
includes: cell thickness, dry weight unity on surface, and concentration of dry
substance unity on surface. The therapy with sympatomimetics,
bronchospasmolitics, hormones do not restore the whole structural and
cytochemical changes of erythrocytes. Therefore, we observed after ZADITEN
administration in both groups significant restoration of erythrocyte membranes.
According to this data, we can judge about the efficiency of the treatment, the
severity of disease and the ability of the prognoses of the disease.
nkandelaki@hotmail.com
33. R. Kapanadze, T. Jorbenadze, N. Jorbenadze Iv. Javakhishvili Tbilisi State University,
Department of Pathology, Georgia.
Myocardium structural-functional and blood
reomorphology changes in autoimmune cardiomiopathy
Summary. It is assumed, that in autoimmune cardiopathy in
myocardium, activity of ferments, which take part in acid-restoration and
hydrolytic processes lowers, quantity of glycogen and ribonucleitics is reduced.
Treatment with the help of “C” favors normalization of metabolism in myocardium.
34. Katsarava V.Sh., Gobachia K.N.,
Chinchaladza A.A., Katsarava L.V.
Acad. V. Pipia Georgian Center of Thoracic Surgery Science and methodologies. Acad. Z. Tskhakaia
Thoracoabdominal clinic.
Perioperational
antibioticoprophylaxis in cases with scary stenosis of larynx and trachea.
Summary.
Surgical treatment remains as method of choice for scary stenosis of
laryngotracheal area. 51(85%) out of 60 patients with laryngotracheal scary
stenosis have been operated using several types of plastic-reconstructive
surgery in Georgina center of thoracic surgery science and methodologies at
Thoracoabdominal clinic in Tbilisi Georgia. Types of surgery implemented.
Circular tracheal resection have been performed in 44 cases and several types of
laryngotracheal plastics have been performed in remained 7 cases. Preoperational
tracheal dilation with rigid bronchoscope have been utilized in 46 patients with
total of 76 procedures performed. Perioperational antibacterial prophylaxis have
been utilized in 37 cases (group 1). 14 patients (group 2) have been operated
without any of perioperational antibacterial therapy. In 3 (8,14%) cases from
group 1 have been observed several postoperational complications, rather then
in group 2 10 (71,1%) cases have been presented with postoperational
complications. Overall mortality rate was 3,9% and all of them from group 2 –
patients operated without antibacterial prophylaxis.
35.
V. Kenchadze, G. Sikharulidze. Medical Institute; A. Robakidze. Chair of Medical
Psychology and Psychiatry of Tbilisi State University.
About interdependence between psychopathology and age at paranoid schizophrenia.
Resume.
Psychic
disorders developed in the period of gerontogenesis represent an issue of great
practical significance in psychiatry.
In our opinion, the significance of the present
research lies in the fact, that the study of the regularity of the course of
schizophrenia for the whole period of its development will most likely give us
an opportunity to define the near and distant prognoses of the desease with
greater precision. On the basis of the results of the research, we shall be
capable of objectively solving all practically important problems related to the
treatment of the desease and its rehabilitation. Moreover, it is possible to
make preliminary conclusions which specify that continuous paranoidal
schizophrenia started at the age of 18-25 is characterised with a much worse
distant prognosis compared to the same desease started at a later age /25-32
/.
36.
M. Kereselidze, N. Chikhladze.
Economic models of medical insurance.
Summary. The article deals with the existing economic
models of medical insurance and their comparative analysis. It also focuses on
those aspects, which are to be taken into account when working out native models
of medical insurance.
37.
S. Khechinashvili, G. Gogniashvili, Z. Lagidze, I. Kevanishvili, Z.
Gamgebeli, Z. Kevanishvili Center of Audiology and Hearing Rehabilitation.
Objective Estimation of Frequency
Discrimination Capacities in Cochlear Implant Recipients
A b s t r a c t
The paradigm of objective estimation of frequency
discrimination facilities in cochlear implant users (CI) has been elaborated.
The idea of the procedure basis on the frequency specific characteristics of
the slow cortical potential (SCP). The tonal stimuli of two different
frequencies are presented to the listener through the loudspeaker at fixed
inter-stimulus intervals. Two referent trials and a single test trial have been
conducted. In the referent trials two SCPs are averaged in two separate
computer channels to the consecutive presentations of two sets of tone bursts of
two different frequencies. In the test trial the tone bursts of both frequencies
are mixed and applied under the same stimulation run alternatively, i.e. one
after another. As in the referent trials, in the test trial the SCPs to the
tone bursts of each frequency are averaged in two separate computer channels.
Two SCPs of the test trial are then compared with two respective SCPs of the
referent trials. In the case of discrimination of the presented frequencies by
the listener, e.g. by the CI recipient, two different populations are
activated in the SCP generating system in the test trial. The actual intervals
between activation of each population, destined for each frequency, are
correspondingly prolonged that is followed by the amplitude increments. The
amplitudes of the test SCPs exceed therefore those of the respective referent
SCPs. In the case of the absence of frequency discrimination, conversely, the
same neural population is triggered under both mono-tonal and bi-tonal
stimulation that is manifested in the amplitude equalities of the respective
test and referent SCPs.
Generally, the adopted procedure is
considered beneficial for precise estimation of frequency discrimination
aptitudes in individual CI users. The objective assessment of discrimination
facilities of applied sound messages could particularly useful in prelingual
patients, especially in young children.
zurag@km.ru ,
gogni@yahoo.com
38. L. Khirseli R.Kharatishvili G.Bagdavadze.
Eye-socket and retro bulbar area phlegmon
S u m m a r y
Eye-socket phlegmon is devoloping from the
odontogene inflammatory processes – near-lying anatomic formations of the
eye-socket. Eye-socket phlegmon is characterized by serious clinical course,
frequent suppurative complications in retrobulbar area, optic nerve atrophy what
often brings to reduction of eyesignt keenness and total blindness.
The Maxillary –Fecial Surgical Department of the
Tbilisi No. 4 Clinical Hospital within the last 6 monthes has been treating 3
patients with diagnosis: Eye-socket phlegmon in retro bulbar area, We carried
out surgical dissection of eye-socket through upper, lower and lateral accesses.
Was carried out Highmorotomy, dissection of retro bulbar athmoid area as well as
complex medicinal treatment.
Two (2) patients lost eyesight; one (1) patient
fully recovered. Conclusion: Our observations permit us to express an opinion
that timely diagnosing and surgical-complex treatment of eye-socket phlegmon and
retro bulbar area makes full recovery possible.
39. Khodeli , Partsakhashvili, Chanturia, Gogatishvili
, Mdivani , Inauri, Ekvtimishvili,
Kruashvili, Machavariani, Inauri.Javakhishvili
State University in Tbilisi. Medical Faculty Department of Normal and
Clinical Human Anatomy.
Connective tissue
layers of temporal area and their clinical importance
Due to the diversity of opinion in the literature
describing temporal area, layered preparation of these areas is carried out on
the adult and infant corpse material. It is confirmed that infectious processes
can easily spread and generalize in soft tissues of infant temporal areas. In
adults, seven connective tissue layers are discovered, which are sharply
delineated, differently isolated, and connected to the neighboring areas. The
consideration of their existence and distinctiveness is necessary for the
prognosis, diagnosis and treatment of the development and expansion of
infectious processes in the area.
40. A.Khomasuridze, MD, N. Maisuradze MD, N. Tabidze,
Cand. M. Sc., Tabidze, Cand.M.
Sc., Zhorandia Research Institute of Human Reproduction.
INTRODUCTION OF
REPRODUCTOLOGY TERMS INTO UNIVERSITY MEDICAL
EDUCATION
Summary
The foundations of Georgian
medical terminology were first laid in 1918 when a
medical faculty was opened at Tbilisi State University. The absence of
Georgian-language medical terms was a great obstacle in the process of training
local medical students. On the initiative and with the participation of Prof. A.
Natishvili and Z. Maisuradze the first Georgian anatomical terminology was
created serving further as a basis for creating
branch terminology in the science of medicine.
In 1994, reproductology (reproduction science)
acquired in Georgia the status of an independent medical discipline under the
class 14.00.50 giving start to collection of relevant information. The
reproductology branch lacks reference information, whereas the demand for it is
permanent growing.
The team of authors offers a
Georgian defining dictionary of reproductology terms on the one hand as
well as the corresponding Russian and Latin equivalents on the other.
The concise Georgian defining dictionary of
reproductive terms is another step forward in the classic university medical
education taking its origins from foundation of the first Tbilisi University
based medical department in 1918 as well as from the Zhordania Research
Institute of Human Reproduction, which since 1958 has been engaged in the
origination and development of the branch of reproductology in Georgia.
41. Khudjadze, Gogniashvili, Kevanishvili,
Tracheal stenosis therapy
by using resection-anastomosis
method.
Abstract
Tracheal stenosis is not
quite frequent nozology , at the same time it is most complicated pathology in
ORL.
The matter is that two
main methods of treatment such are dilatation and resection-anastomosis are
connected with a great complicate and it requires highly skilled surgeries and
anesthesiologists.
From ethiological
factors must be mentioned trauma and scald although posttracheotomic stenosis
must be separated. There are compensative and decompensative levels of stenosis,
but mostly we deal with compensative dyspnoea what gives us oportunity to plan
treatment tactics beforehand.
Our report is devoted
to a surgical treating of posttracheotomic stenosis by using resection-anastomosis
method. 36 years man was operated and observed after operation during five
months.
42.
Khvadagiani
M.G. ORL Clinic of the Medical Academy,
Tbilisi, Georgia. Therapy for
poliposis of nose cavity.
The use of
rigid endoscopes for investigation of nasal sinuses and functional
endonasal endoscopy for
the treatment of poliposis are standard approach.
As a first step we used
antihistamin, antibacterial and
antiiflamatury treatment for the patients with
poliposis. After 3-5 weeks we reevaluated of patients and than according
to results consrvative treatment was continued or
endonasal endoscopic
microsurgery was sugested. From 77 patients treated
by this in 21 cases consrvative
treatment was effective, but 51 there was need for complex treatment modality
(conservative + microsurgery). In 5 cases there was the need for repeated
microsurgical intervention and only one patient underwent radical surgery.
The complex therapy is reducing
amount of patients whose need radical operation.
E-mail: endolory_biko@yahoo.com
43. M. Kiladze, T. Chagiashvili, V. Abuladze. Institute of Surgery.
Gastroesophagial reflux disease in Georgia.
Abstract. GERD is a common
gastrointenstinal disoder. The most common symptom is heartburn, which can be
managed successful in many patients with lifestyle modifications and
nonprescription medications. Prescription therapy is indicated for patients in
whom lifestyle modifications and nonprescription medications are not effective
in controlling symptoms, or for patients evidence of esophageal tissue
damage.Effective treatment of such patients is especially important because
untreated cronic GERD is associated with a namber of potentially serious
complications,including esophageals ulcers, bleeding, strinctures, and Barrett’s
esophagus leading to adenocarcinoma
44. G.Kipiani. Tbilisi State
Medical University.Department of Pediatric Stomatology and Prevention of denal Diseases.
Peculiaritis of
the distribution of T and B limfocytes in tonzills during the different degrees of dental caries
activity.
On the basis of
clinical and experimental studies of 64 cases of children after tonzillectotomy quantitativ
disribution of CD3+T andCD20+B limphocytes in tonyills during the various
degrees of activity of
dental caries have been studied.The research established quantitative
peculiarities of CD3+T andCD20+B
limphocytes in tonyills in case of dental caries.Results of the study allow us to conceive the
the of theT and B limphocytes in the accomplisment of primary and secondary immune reactions in
the palatin tonzil,which gives us certain basis to evaluate in right way the
role of the chronic
pathologies of palatin tonzills in the pathogenesis of dental caries
45.
K. Kipiani, P. Ubilava. Bokhua Centre of Angiology and vessel
Surgery, Tbilisi.
Analyses outcomes in surgical treatement
of infrarenal abdominal aortic aneurysms.
Summary. The paper analyses outcomes in surgical treatement
of infrarenal abdominal aortic aneurysms, undergone surgery at the N. Bochua
Centre of Angiology and Vascular Surgery in 1991 to 2001. A total of 42 patients
aged 30-75 years were studied. The paper provides evidence for the association
of outcomes with type of reconstruction, continuity of surgery and volume of
hemorrage.
46. N.A. Kiria
Causes of lethal outcomes in-patients with
pulmonary TB and their analysis
Summary
70 lethal outcomes in
inpatients with respiratory TB were analyzed. It was shown that TB progress
leading to pulmonary and cardial insufficiency was the most frequent causes of
the lethal outcomes. Then followed Pulmonology hemorrhage.
47.
M. Kiviladze, G.
Menabde, T. Nemsadze, D. Jankhoteli, M. Gersamia.
Furthev Results of Surgical
Treatment of Lower Prognatism
Summary.
We offer a new method of surgical
treatment of lower prognathysm. Vertical osteotomy of the branches of lower jaw
dawn to the lower third part is done, which is followed by horizontal osteotomy
up to the first molar. The method is termed vertical-horizontal osteotomy of
lower jaw. In the process of the upper prognation treatment, for the improvement
of the osteotomical fragments by means of wire stitches or microplastic
osteosynthesis is proposed.
48.
Kopadze T., Azmaiparasvili T.;
Beritasvili Institute of Physiology, Tbilsi, Georgia;
“Verbal
disorders after basal ganglia lesion: Diashizis or specific subcortical syndrom?”
49.
Kordzaya.
Academy of Classical and Traditional
Medicine Tbilisi, Georgia.
"TRADITIONAL
MEDICINE, INTEGRATIVE MEDICAL APPROACH: REALITY AND GENERAL TENDENCY".
50 .G. Kukhalashvili, M. Kereselidze, N. Chikhladze.
Stages of data research in medical
marketing.
Summary.
The article deals with the main
stages of marketing research, as well as significance of statistic indices of
healthcare in the process of analysis of possibilities of the medical market.
51.
A.
Kurtanidze, M. Kvantaliani.
Attention Deficiti
Hyperactiviti Disorder (ADHD)
Summary
ADHD, once called hyperkinesis or minimal brain
dysfunction, is one of the most common mental disorders among children . It
affects 3 to 5 percent of all children, perhaps as many as 2 million American
children. Two to three times more boys than girls are affected. On the average,
at least one child in every classroom in the United States needs help for the
disorder. ADHD often continues into adolescence and adulthood, and can cause a
lifetime of frustrated dreams and emotional pain.
But there is help . . . and hope. In the last
decade, scientists have learned much about the course of the disorder and are
now able to identify and treat children, adolescents and adults who have it. A
variety of medications, behavior-changing therapies, and educational options are
already available to help people with ADHD focus their attention, build
self-esteem, and function in new ways.
e-mail address: ina@posta.ge
52.
T. Lobjhanidze. Public Health
Department of Georgia.
PUBLIC HEALTH
SERVICE FORMATION AND DEVELOPMENT STRATEGY IN GEORGIA.
Public Health -
State obligations system, directed to defend and rehabilitation of mental and
physical status of human, and support the environment health, healthy habits,
and health promotion.
The main goal, for
which public health services were created in XIX century, is to fight against
infectious diseases and this sphere remains to be priority today. that’s why the
reorganization of sanitarian–epidemiological service was one of very significant
goals of reform, especially it concerns to disease surveillance system based on
laboratory services. Together the strengthening of laboratory services and
adapting of high technologies, it's very necessary to introduce and effectively
use of modern epidemiological methods, which gives us possibilities for
assessment influences of harmful environmental factors on population, for study
the reasons and fight against them.
The second main
function of public health is providing the population with healthy living and
working environment.
The third function
is provision of special groups of population with health care services
Healthy life style
establishment- is the forth function of public health services
The fifth function
is the effective primary health care.
And sixth function
is – to conduct the necessary investigations for elaborating of the appropriate
strategy and tactics of realization.
53 .N.Mamamtavrishvili, T.Sanikidze, G.Tabidze,
M.Iakobashvili, E.Narsia, M.Mindadze, M.Kvavilashvili.
Tsinamdzgwrishvili's
Institute of
Cardiology, Institute of Experimental and
Clinical Medicine, Tbilisi State Medical University.
Free radical
oxidative processes in chronic heart failure
Patients with
chronic heart failure (II, III NYHA) were found to have significant reduction of
Fe3+ transferin with Fe2+ accumulation and the enhancement
of lipid peroxydation.
This is significant
reduction of NO concentrations, possibly as a result of low expression by
endothelial cells of NO and peroxynitrite transformation of the latter, or,
alternatively, HbNO and FeSNO complex formation in the blood of patients with
chronic heart failure
54.N Mandjavidze. Dental Clinic Royal-dent. Tbilisi.
After adhesion and penetration into tooth
canal tissues with the help of scanning electronic microscope.
Summary
The mechanism of
intraradical use
of dentin adhesive systems and etching acids of hard tissues is unknown today.
Therefore our research was aimed at studying the degree of their adhesion and
penetration into tooth canal tissues with the help of scanning electronic
microscope.
3 various adhesives AQ Bond (Morita), Etch & Prime
(Degussa) and Prime & Bond NT (Dentsply)
were used in the process of the research. 16% EDTA and 35% H3PO4
were selected as etching components. Human extracted teeth were used as objects
of the research. The sections of teeth were studied with scanning electronic
microscope after their treatment with the above-mentioned systems.
Adhesive system Etch & Prime 3.0 (Degussa)
together with 16% EDTA demonstrated the best qualities. Dissolution of smear
layer on the canal wall after the operation of EDTA and the exposition of dentin
apertures stimulated penetration of the adhesive into deep layers of dentins and
formation of wide hybrid zones.
55.
G. Menabde, R. Kalmakhelidze, L.Khirseli, Z. Machavariani, D.
Andguladze. State Medical Academy of Georgia, Surgical and orthopedic dental
chair.
Furnishing a Trauma
Allopethy by Means of Local Plastic
Summary
Operational method of
treatment of allopathy by means of silicon expander
is discussed in the article. Dose straching of skin
is performed with an expander and recieved material
is used tofurnish the deffects.
56.
Meparishvili. Khurodze, Chkhobadze, Dzidziguri, Chigogidze, Managadze.
Tbilisi State University, National Centre of Urology. Studying
of rat`s kidney albuminous
factor on human Renal cell carcinoma.
Summary
It has been
established that kidney cells of a mature white rat include inhibiting
albuminous factor for
epiteliocytes` reproduction. It's shown that the effect of the mentioned
factor is performed at the level of genes` original activity regulation.
Rat`s kidney albuminous
factor reveals an inhibiting effect on the nuclear transcript activity isolated
from the human cells of Renal cell carcinoma (light cellular variant) as well.
The factor`s inhibiting effect has not been revealed
at the area far from a tumor center that may be conditioned by the limitation of
target genes` exscess to mentioned cells.
57.
M. Mestiashvili, N. Kurashvili, K.
Gamkrelidze. Research Institute of psychiatry.
The role of biological and
socio-psychological factors (factors of risk groups)
in occurrence of deviation and delinquent behavior at children and teenagers.
Summary
In the work there are submitted children's groups of increased risk, which
are formed at children in the preschool and school period under influence of
negative biological and socio-psychological factors, mainly with sub
clinical signs and with demonstration in pubertal period in the form of
delinquency. There are developed early concrete and differential preventive
actions of social disadaptation.
58.
M. Mestiashvili, D. Zurabashvili, M. Tsirekidze. Research Institute of psychiatry, Tbilisi State
Medical Institute, Chair of Psychiatry and Medical Psychology.
Addictive variant of teenager's delinquency.
Summary
For last years the special urgency is got with a
problem of deviant behavior among children and teenagers. Among various forms of
dissocial frustration, basically, it is submitted delinquent behavior.
Delinquency more and more becomes complicated with heavy aggressive, unethical
and immoral displays, early alcoholization, glue sniffing, "rejuvenescence" of
an addiction, and that is especially important, frequent illegal behavior and
criminal acts. Abovementioned manifestations are mainly shown at addictive
variant of delinquency. At teenage age it is not actual generated addiction, but
the malicious use of narcotics and toxic substances, when the expressed
individual physical dependence is not marked and disease is not developed yet.
The mane purpose of research was to study addictive variant of delinquency,
developed under influence of negative microsocium and chronically psycho
traumatic factors. Among the investigated 50 teenagers, factors of negative
microsocium are revealed in 41 %, and chronically psycho traumatic factors - 59
%. Proceeding from the analysis of a material, types disharmonic families were
showed in the following sequence: incomplete family - 53 %, rigid pseudosolidar
family - 21 %, breaking up family - 9 %, the broken family - 3 %.
Among the types of upbringing hipopatronage have been established in 53 %, the
hyper patronage - 12 %, inconsistent type of upbringing - 15 %, changing of
upbringing methods in connection with dynamics of home-life - 15 %, upbringing
as family "idol" - 6 %. Among family conflicts on the forefront there came
intensive family conflicts of-76 %, then incidental - 16 % and easy family
conflicts - 8 % act.
Character
accentuation, psychopath, pathological pubertal crisis, asinqronous rate of
maturing, mainly an acceleration, can be ranked as factors promoting development
of delinquency and, in particular, its addictive variant.
Illegal behavior at addictive variant of
delinquency there is established in 35 %, and criminal acts - in 6 %.
In addictive variant, prevail teenagers with
underdeveloped moral - ethical standards and absence of correct social
motivation, though it is necessary to note, that social adaptation is not broken
for long time.
The orientation of addictive teenagers behavior is
determined by aspiration to get in "narcomanic" campaign and to "associate" in
it. They exaggeratedly imitate the leader of antisocial group,
participate in getting alcoholic drinks and toxic means and, in general, in the
organization "addictive climate ". The certain part of teenagers shows ability
to analyze critically the behavior and frequently keeps an opportunity of
prognostic estimation of addictive behavior consequences
59.
T. Mikadze, O.
Darjania.
Summary
The main mission of
the orthodontia is not only formation of perfect dentition, but also improving
general hygienical condition of the mouth, the hard fissures and periodontal
60..L.Mirzashvili, G.Katsitadse,
N.Chavchanidse, N.Lobjanidse, T.Giorgobiani. Analyses of self-poisoning events in
different regions of Georgia (Tbilisi, Batumi, Gori) in the postdisaster period.
Summary
Toxicological events in Georgia were analysed. It was found, that the quantity
of self-poisonings increases in the postdisaster period.
Datas are different for the
different regions of Georgia.
61 .D. Mkhitariani, G. Kapanadze, L. Dzidziguri, M. Giorgobiani, Z. Vadachkoria,
D. Dzidziguri. Tbilisi State University, Tbilisi State Medical University.
Summary
The influence of
prevention by immunomodulator and sedative premedication on the genes expression
in cells of lung and liver tissues of experimental animals (white rat) at
inhalative anesthesia with halotane was studied. It was established that
inhalative anesthesia via halotane inhibits the process of transcription only in
nuclei of lung cells. The inhibition effect stipulated by anesthesia is removed
after premedication with diazepam. The analogous effect was observed also after
prevention via plaferone. At thf same time the inhibition of RNA- synthesis
takes place in cells of both tissues by simultaneous application of
abovementioned drugs.
62.
B. Mosidze, K. Kupreishvili, D.
Mikeladze. National Centre of Surgery, Tbilisi.
The model of the “bloodless” liver in
experiment in vivo
The model of the “bloodless”
liver in vivo has been established in our experiments. The surgery consists of
the following stages : 1) cutting the liver of the general blob
circulation by means of a roundabout shunting without using the one - way
pump; 2) conservation of the liver; 3) spontaneous
intervention on the liver parenchyma; 4) revascularization.
63.
Nakashidze I., Chikovani T., Sanikidze T.,
Bakhutashvili V., Kevlishvili O.Institute of Medical Biotechnology, Tbilisi, Georgia.
Peculiarity and
correction oxidant stress in the experimental traumatic shock
Summary
Aim: The goal of our research was to investigate the
changes of oxidative–antioxidative systems occurred during the experimental
traumatic shock.
Methods: Experiment was held on 30 white rats weighing 200gr. Traumatic shock
was induced by the injury of soft tissues according to the Cannon method. The
decreasing of the arterial blood pressure was concomitant of the shock
development. 60 mm of the mercury line was the threshold of the shock
development. 15 minutes later (from the shock development) the first group
animals were injected by the saline 0,3ml intraperitoneum. The animals of the
second group were injected by Plaferon LB 0,6 mg on 0,3 ml the saline. 30
minutes later from injections, rats were killed. The blood was taken from the
jugular vein and was studied by biochemical and
electron spin resonance (ESR) spectrometry
technique on radiospectrometer RE-1307.
Results:
The study
revealed that traumatic shock is characterized by activation of lipid
peroxidation, hyperproduction of free radicals and inhibition of endogenic
antioxidant system. Plaferon
LB significantly decreases processes of lipid peroxidation and improved
antioxidative capacity of blood.
64.
Nakashidze J. Kh. Nakashidze M.G. Nakashidze
M.J. Batumi N1 Hospital
Main aspects
of diagnosis and treatment of thoracic injuries
In 1997-2002
years 85 patients with thoracal injuries were admitted our hospital.Surgical
operations were performed in 52 cases-pneumoraphy-7, cardioraphy-3, ligation of
aa. Intercostals et mamaria inferna-4,
pericardioraphy-1, lobectomy-1, diaphragmoraphy-7. In 25 cases invasion was
limited as surgical cleansing of wound and drainage of pleural cavity.
We suppose
that surgical invasion must be maximally limited- with strictly according to the
indications.
65.
N. Naneishvili, N. Kurashvili. Research institute of Psychiatry.
Disasters and Human
The explosion of electrical
station of 2001 was important for same reasons: the explosion itself is a big
stress because it’s power and strength is egual to explosion barotrauma and it
causes the mental desorders of craniocerebral trauma;
The impact of the substance after
explosion is as a toxical factor:
The people settled their next to the
power station(The technical and hygiene living condition were rejected)
They had before Post-Traumatic Stress
Disorder(PTSD) and they have been living in that teritory under the fear.
There were following traumatic stress
factors:
1) Psychophysiological
stressors-strange and terrifying noise,screams of agony,scattering of dust and
the strange substances and pain due to injuries.
2)
Information stressors(what is going on? how
can I escape? where are my parents or children)
3)
Emotional stressors(threat of death. the
fear for one’s self and for parents, vital feeling, hopeless)
4)
Social stressors (the demage of house ) and
another material harm
The results showd that after exlosion
80% of those inhibitants have PTSD, 10%-Depression,
8%- Phobic syndrome.Almost everyone
have the signs of barotraume.
As a result of this ecological
equilibrium was disturbed and traditional living conditions were violated.
The traumatization of these
people are in progress for 15 years and the top level of it was 22 Desember,when
some stress disorders were cumulated which worsening their health state.
Contributing to the existing economic
problems consequences of the above mentioned are: desocialization, desadabtation,
PTSD, , anxiety, behavior disorders, chronic personology disorders
At present the traumatic stress
factor still remains, because they live in the same area.
The study reveald that mental state
in these groups is critical and needs urgent management and support, more active
complex help in medical and social field.
66 . M. Nemsadze,
T. Churadze, D. Gordeladze, K. Barabadze.The prognosis
criterion of premiturely new-born viability
The prematurely
new-born birth and upon their viability has a great influence the fetal
(gestational) age and body mass buring the birth, the uterus evoluation
retention mother’s age, gynecological, sometic patology, keen infectional
diseases during the pregnancy and psycho-social envioronment.
The prematurely
new-born death shortening reserves are the following: young generation medical
cultural rise, undesirable pregnancy avoid, introduction of family planning,
keen infectional diseases prophylaxis, chronic diseases adequate ruling, fertile
age women examination on “Torch” infections, life incompatible defect foetus
elimination, there for the premature childbirth 2 percent shortening 9 percent
shortens the infant mortality.
67. Nemsadze T.,
Menabde G., Apridonidze K., Kapanadze R, Kiviladze M, Khirseli, Asatiani G. Georgian
State Medical Academy Department of Orthopedic and Surgical Dentistry.
Use of
Plasmatic irradiator in complex treatment of odontogenic purulent-inflammatory
diseases of Maxillo-facial region.
SUMMARY
Aim of the
work is to study the possibilities of use of plasmatic stream with the medical
aim. The work of experimental and clinical character. By means of experiments
carried out on the rabbits the influence of plasmatic stream on microorganism,
as well its influence on the processes of reparative regeneration. The analysis
of the results obtained have shown that the plasmatic radiation has a powerful
bactericidal affect, it causes the stimulation of reparative regeneration in
soft tissues of the organism.
The use of
plasmatic stream in a complex treatment of above indicated diseases considerably
speeds up the time of treatment and has a grate economical effect.
68.
T.J. Nijaradze. A.Natishvili
Institute of experimental morphology Georgian Academy of Science, Tbilisi,
Georgia.
The effect of
immaturity factor on neutrophils function.
Summary
This
study investigated the reactions of neutrophil in immature newborns during
neonate sepsis. The amount of neutrophilic granulocytes
(NG) with active phagocytosis (absorbtion and killing of bacterial antigen) –
“classical’’ type of reactivity were studied. The “paradoxicalal” reaction –
necrosis (granulolysis, incomplete phagacytosis) also is demon-strated in
peripheral blood specimens. The results
suggest that immature induces the different functional activity of NG in
newborns
69.
V. Papitashcvili, I. Siradze.
Tbilisi medical academy.
Wilson's disease modern methods of diagnostics and
treatment (clinical sing)
Summary
Our clinical
sign is demostration of lately psichiatric and soft neurologic manifestation (whithout
liver disease), positive MRI scans results (basal ganglions), and favorable
effect of penicillamine and galzine. Wilson's disease is autosomal recessive
disorder (molecular deffect within a copper-transporting ATPase) Clinical
manifestation is usually present with hepatic, neurologic, and psychiatric
problems
.70
. A. Popiashvili.
Classical and traditional medical academy.
Helio
сomposite
filling material “Synergy”
Summary
There are many problems during the restoration of
a tooth: selection of the suitable color, defence of the smooth surface for a
long time, invisible border. Our purpose is to define which filling material:
“Synergy”, “Prodigy” or “Kharizma” can decide these
problems.63 teeth were restored. 10 months’ observation has shown that
‘’Coltene’’ ’s new helio
сomposite
filling material “Synergy” better decides all these problems
71.
Sh. Sabanadze. National Center of
Tuberculous and Lung Diseases. First therapeutic
division.
Tuberculous Meningitis in Georgia
Tuberculous
meningitis remains one of the severest and most serious diseases among various
forms of tuberculosis up today.
The prognosis for the
disease depends on the timely diagnosing and conducting adequate antituberculous
treatment. The relatively low percentage of the cases of tuberculous meningitis
and relatively high percentage of tuberculous meningoencephalitis testify to the
belated diagnosing. The bulk of the deceased patients are the ones with belated
diagnoses.
In the division of
tuberculous meningitis at the National Center of Tuberculous and Lung Diseases
236 patients were admitted from 1995 to 2002. Among them 208 patients were
diagnosed as tuberculous meningitis and tuberculous meningoencephalitis. In 28
cases the diagnoses of tuberculous meningitis were not confirmed. They were
diagnosed later as virus meningitis, disturbances of blood circulation in brain,
volume processes in brain and the patients were transferred to the adequate
clinics.
From 208 patients 155
ones were cured, 11 ones were discharged in unchanged states, 7 ones – with
improved states, in 2 cases we had aggravation in the form of central nervous
system tuberculosis, 35 patients died, among them 28 ones in the very first days
of their admission, and 7 ones due to ineffective treatments.
72.
M. Shanidze, K. Kandelaki.
To a
question of treatment of
chronical recidivating aphtos stomatitis
S u m m a r y
The effect caused by using of new preparation - “ Phagobioderm-denta” in patients with chronical recidivating aphtos stomatitis
is well. It has painrealeve and antiinflamation actions, also increasing
regeneration and shorting time of treatment. It has no side effects, enough easy
to use and not expensive for patients
73.
V.Sulkhanishvili,,V.Bakuradze,G.Amiridze,G.Khadagiani,D.Chavchanidze,
T.Chigogidze, V.Bakkhutashvili. National Center of Urology,
Tbilisi, Georgia
Protective Effect of Plaferon in Acute Thermal Ischemia of the Kidney
Summary
Development of the drugs with the effects against ischemia of the kidney is the
great challenge. Plaferon was developed at the Institute of Biotechnology
(Tbilisi, Georgia; director – V. Bakhutashvili), that was successfully used in
clinical practice during last decade. Plaferon is produced from the amnion of
the human placenta, undergoes special treatment to avoid contamination by
hepatitis B and C viruses as well as by HIV.
The aim of our study was to
stress the effect of Plaferon- in experimental setting on renal function,
structure, hemodynamics and metabolism in case of ischemia for 60 min and 90
min. Comparison has been made between the local hypothermia and
pharmacoprotection by Plaferon LB as a protector against renal ischemia.
The experiments were carried out
on 100 wistar rats (weigh 150-200 g) and 72 mongrel dogs (weight 15-24 kg). Our studies revealed that
Plaferon is the potent anti-ischemic and protective drug against renal
ischemia. The survival of animals was high – the evidence of positive activity
of Plaferon
74.
Tabidze, Mamamtavrishvili, Iakobashvili, T. Chavchanidze,
Narsia, Tsibadze, Abashidze, Bakhtadze, L. Chavchanidze, Burduli.
Tsinamdzgvrishvili Institute of cardiology, Tbilisi State University.
Peculiarity of heart chronic failure therapy with
Reniteck on arterial hypertension background.
S U M M A R Y
The aim of the research was to study
whether ACE-inhibitors may be used in patients with chronic heart failure (CHF)
of high functional classes (FC) and arterial hypotension. The findings support
the fact that arterial hypotension is of relative significance in patients with
CHF when the max effective doses of ACE-inhibitors are chosen. The development
of antihypertensive responces to ACE-inhibitors in patients with baseline
hypotension without significant clinical manifestations and no less then 85 mm
Hg SBP reduction produces no negetive effect on central hemodynamic parameters
and exercise tolerance.
75. T.
Tarkashvili,
T. Chigogidze.I.
Javakhishvili
Tbilisi State UniversityUrology
Department, Georgian
Rustavi
Metallurgical Work’s Hospital.
Regarding
the methods of modification
transvesical
adenomectomy
Summary
The article analysis the
methods of adenomectomy.
The new view is given, possibilities of which are analyzed on the example of 23
patients.
76 .
Tavberidze , E . Gotsadze, N
.Tavberidze. O. Gudushauri’s Centre of Orthopedic and Traumatology, Sepsis
Centre, Tbilisi, Georgia
Complex Treatment of Long Bones Segmental and Soft Tissue Septical
Defects of Upper Limb.
Summary.
The study cohort comprised 26 patients, who were treated in O.Gudushauri
Centre of Orthopedic and Traumatology and Sepsis centre of Georgia from
1986 to 2002 years, with long bones segmental and soft tissues septical
defects of upper limb. Average age 40 years . From 26 patients, .23 was
male and 3 female. 59% of patients were with nonunion fractures, after high
energy open trauma. 41 % of patients had complications after
combine fractures by non stabile osteosinthesis. All patients before
our treatment, spend in other clinics from 1 month to 1 year. Some of
them had from 1 to 3 operations without result. In 1981-86 years in 68 % cases grew up staphylococci microbes,
the gram-negative infection was 32%. In present we had another information
from microbiology laboratory of sepsis centre, staphylococci flora grew in
64%, gram-negative microbes - in 36 %, effectiveness of popular antibiotic
ciprofloxsacilline - in 63 %, penicciline – in 16%,amoxicilline – in 12%.
Before operations we used antibiotics after test with pathogenic microbes
from the wound. From 152 cases of grafting long bones septical defects with
cortical cancellous and spongioza auto grafts upper limb was in 26 cases
(17%). In 6 cases there was skin and soft tissue defects of arm and
forearm. To covered soft tissue defects in 2 cases with big area of skin
defect, we use free vascularized abdominal flap, in other cases we use free
flap of skin. In 5 cases bone grafting used before skin plastic. The
positive result after our treatment we watch in 24 cases, in 1 patient
after gunshot trauma of arm the bone was nonunion, without infection, in 1
case was recidive of osteomielit.
77.
B.TKESHELASHVILI
“Academician Chachava Scientific Research Institute
of Perinatal Medicine, Obstetrics and Gynecology’’.
Tbilisi. Georgia.
ADAPTATIONAL MECHANISMS OF METABOLIC
SUPPLY OF PHYSIOLOGICAL PREGNANCY
Three stages of gestation were distinguished in the dynamics of
physiological pregnancy on the basis of investigating the reaction of the basic
characteristics of oxygen-transported systems (erythron and
hemocirculation):
I.
The begining of the gestation dominant
formation, reflecting the process of energy expenditure optimization,
corresponds to the phase of urgent adaptation.
II. |
